Publications
Management of Undifferentiated Embryonal Sarcoma of the Liver: A Pediatric Surgical Oncology Research Collaborative Study
Kastenberg ZJ, Short SS, Riehle KJ, Utria A, Lautz TB, Ott KC, Murphy AJ, Mansfield S, Lal DR, Hallis B, Murphy JT, Roach JP, Polites SF, Beckhorn C, Tracy ET, Fialkowski EA, Seemann NM, Bütter AM, Rich BS, Glick RD, Bondoc AJ, Ofori-Atta BS, Presson AP, Chen SY, Zamora AK, Kim ES, Vasudevan S, Rinehardt HN, Malek MM, Lapidus-Krol E, Putra J, Superina RA, Langham MR, Meyers RL, Tiao G, Dasgupta R, Baertschiger R
Pediatric Blood & Cancer. 2024;e30975. Online ahead of print.
Comparison of Outcomes between Surveillance Ultrasound and Completion Lymph Node Dissection in Children and Adolescents with Sentinel Lymph Node Positive Cutaneous Melanoma
Scoville S, Stanek JR, Rinehardt H, Sutthatarn P, Abdelhafeez A, Talbot L, Malek M, Leraas HJ, Tracy E, Chen S, Kim ES, Lotakis D, Ehrlich PF, Favela JG, Le HD, Davidson J, Wilson CA, Seemann NM, Osman Y, Piche N, Hoang V, Petroze RT, Polites SF, McKay KG, Correa H, Lovvorn HN, Lee Y, Balagani A, Dasgupta R, Aldrink JH.
Ann Surg. 2023 July 24. Doi: 10.1097/SLA.0000000000006022. Online ahead of print. (PMID 37479570)
Management and Outcomes of Wilms Tumor with Suprarenal Intravascular Extension: A
Pediatric Surgical Oncology Research Collaborative Study
Naik-Mathuria B, Utria AF, Ehrlich PF, Aldrink JH, Murphy AJ, Lautz T, Dasgupta R, Short SS, Lovvorn HN 3rd, Kim ES, Newman E, Lal DR, Rich BS, Piché N, Kastenberg ZJ, Malek MM, Glick RD, Petroze RT, Polites SF, Whitlock R, Alore E, Sutthatarn P, Chen SY, Wong-Michalak S, Romao RL, Al-Hadidi A, Rubalcava NS, Marquart JP, Gainer H, Johnson M, Boehmer C, Rinehardt H, Seemann NM, Davidson J, Polcz V, Lund SB, McKay KG, Correa H, Rothstein DH.
Ann Surg. 2023 Jun 2. doi: 10.1097/SLA.0000000000005921. Online ahead of print. PMID: 37264925.
Incidence and Management of Pleural Effusions in Patients with Wilms Tumor: A Pediatric Surgical Oncology Research Collaborative Study
Al-Hadidi A, Rinehardt HN, Sutthatarn P, Talbot LJ, Murphy AJ, Whitlock R, Condon S, Naik-Mathuria B, Utria AF, Rothstein DH, Chen SY, Wong-Michalak S, Kim ES, Short SS, Meyers RL, Kastenberg ZJ, Johnston ME 2nd, Zens T, Dasgupta R, Malek MM, Calabro K, Piché N, Callas H, Lautz TB, McKay K, Lovvorn HN, Commander SJ, Tracy ET, Lund SB, Polites SF, Davidson J, Dhooma J, Seemann NM, Marquart JP, Gainer H, Lal DR, Rich BS, Glick RD, Maloney L, Radu S, Fialkowski EA, Kwok PE, Romao RL, Rubalcava N, Ehrlich PF, Newman E, Diehl T, Le HD, Polcz V, Petroze RT, Stanek J, Aldrink JH.
Int J Cancer. 2022 Jun 24. doi: 10.1002/ijc.34188. Online ahead of print. (PMID 35748343)
Interhospital variability in localization techniques for small pulmonary nodules in children: A pediatric surgical oncology research collaborative study.
Morgan KM, Anderson KT, Johnston ME, Dasgupta R, Crowley JJ, Fahy AS, Lapidus-Krol E, Baertschiger RM, Lautz TB, Many BT, Marquart JP, Gainer H, Lal DR, Rich BS, Glick RD, MacArthur TA, Polites SF, Kastenberg ZJ, Short SS, Meyers RL, Talbot L, Abdelhafeez A, Prajapati H, Davidoff AM, Rubaclava N, Newman E, Ehrlich PF, Rothstein DH, Roach JP, Ladd P, Janek KC, Le HD, Leraas HJ, Tracy ET, Bisset L, Mora MC, Warren P, Aldrink JH, Malek MM.
Journal of Pediatric Surgery 2022 Jan;
Histologic type predicts disparate outcomes in pediatric hepatocellular neoplasms: A Pediatric Surgical Oncology Research Collaborative study.
Short SS, Kastenberg ZJ, Wei G, Bondoc A, Dasgupta R, Tiao GM, Watters E, Heaton TE, Lotakis D, La Quaglia MP, Murphy AJ, Davidoff AM, Mansfield SA, Langham MR, Lautz TB, Superina RA, Ott KC, Malek MM, Morgan KM, Kim ES, Zamora A, Lascano D, Roach J, Murphy JT, Rothstein DH, Vasudevan SA, Whitlock R, Lal DR, Hallis B, Bütter A, Baertschiger RM, Lapidus-Krol E, Putra J, Tracy ER, Aldrink JH, Apfeld J, Le HD, Park KY, Rich BS, Glick RD, Fialkowski EA, Utria AF, Meyers RL, Riehle KJ.
Cancer 2022 May; [PMID: 35561331, 35561331]
Inflammatory Myofibroblastic Tumor: A Multi‐Institutional Study from the Pediatric Surgical Oncology Research Collaborative
Rich BS, Fishbein J, Lautz T, Rubalcava NS, Kartal T, Newman E, Wok PE, Romao RL, Whitlock R, Naik-Mathuria B, Polites SF, Løfberg K, Lascano D, Kim E, Davidson J, Bütter A, Kastenberg ZJ, Short SS, Meyers RL, Mastropolo R, Malek MM, Weller J, Irfan A, Rhee DS, Utria AF, Rothstein DH, Riehle K, Commander SJ, Tracy E, Becktell K, Hallis B, Lal D, Li O, Dal-Soglio DB, Piché N, Gomez Quevedo O, Murphy AJ, Davidoff AM, Cooke Barber J, Watters E, Dasgupta R, Glick RD
International Journal of Cancer 2022 May;
Implications of Tumor Characteristics and Treatment Modality on Local Recurrence and Functional Outcomes in Children with Chest Wall Sarcoma: A Pediatric Surgical Oncology Research Collaborative Study
Harris CJ, Helenowski I, Murphy AJ, Mansfield SA, LaQuaglia MP, Cavalli M, Cooke-Barber J, Donaher A, Kim ES, Zobel M, Goodhue CJ, Aldrink JH, Richards H, Malek MM, Kalsi R, Fialkowski EA, Short SS, Bleicher J, Meyers RL, Piche N, Joharifard S, Troutt M, Dasgupta R, Lautz TB
Ann Surg 2020 Nov 4. doi: 10.1097/SLA.0000000000004579.
(PMID 33156070)
In this review of 175 children with sarcoma of the chest wall, most common diagnoses were Ewing sarcoma (67%) and osteosarcoma (9%). Surgical resection was performed in 85% and radiation in 55%. A median of 2 ribs were resected (IQR = 1-3), and number of ribs resected did not correlate with margin status (p = 0.36). Local recurrence occurred in 23% and margin status was the only predictive factor (HR 2.24, p = 0.039). With a median follow-up of 5 years, 13% developed scoliosis (median Cobb angle 26) and 5% required corrective spine surgery. Scoliosis was associated with posterior rib resection (HR 8.43; p = 0.003) and increased number of ribs resected (HR 1.78; p = 0.02). Overall, patient-reported quality of life is not impaired following chest wall tumor resection.
Appendectomy Versus Observation for Appendicitis in Neutropenic Children With Cancer
Many BT, Lautz TB, Dobroszi S, Wilkinson KH, Rossoff J, Le-Nguyen A, Dakhallah N, Piche N, Weinschenk W, Cooke-Barber J, Goodhue C, Zamora A, Kim ES, Talkbot LJ, Gomez Quevedo O, Murphy AJ, Commander SJ, Tracy ET, Short SS, Meyers RL, Rinehardt HN, Aldrink JH, Heaton TE, Ortiz MV, Baertschiger R, Wong KE, Lapidus-Krol E, Butter A, Davidon J, Stark R, Ramaraj A, Malek M, Mastropolo R, Morgan K, Murphy JT, Janek K, Le HD, Dasgupta R, Lal D, and the Pediatric Surgical Oncology Research Collaborative
Pediatrics 2021 Feb;147(2):e2020027797. doi: 10.1542/peds.2020-027797.
(PMID 33504609)
In this review of 66 pediatric patients with neutropenic appendicitis from oncologic treatment, upfront appendectomy resulted in lower complication rates, reduced LOS, and fewer alterations in chemotherapy regimens compared to initial nonoperative management.
Pneumonectomy for Pediatric Tumors - A Pediatric Surgical Oncology Research Collaborative Study
Polites SF, Heaton TE, LaQuaglia MP, Kim ES, Barry WE, Goodhue CJ, Murphy AJ, Davidoff AM, Langham MR, Meyers RL, Short SS, Lautz TB, Glick RD, Vasudevan SA, Bence CM, Lal DR, Baertschiger RM, Emr B, Malek MM, Dasgupta R.
Ann Surg. 2020 Mar 20. doi: 10.1097/SLA.0000000000003795
(PMID 32209902)
This represents the largest study of children who required pneumonectomy, or removal of one complete lung. We found that the procedures were well tolerated and two-thirds of patients remained alive and with good pulmonary function one year after surgery.
Optimization of Percutaneous Biopsy for Diagnosis and Pretreatment Risk Assessment of Neuroblastoma
Overman RE, Kartal TT, Cunningham AJ, Fialkowski EA, Naik-Mathuria BJ, Vasudevan SA, Malek MM, Kalsi R, Le HD, Stafford LC, Lautz TB, Many BT, Jones RE, Bütter A, Davidson J, Williams A, Dasgupta R, Lewis J, Troutt M, Aldrink JH, Mansfield SA, Lal DR, Xiao J, Meyers RL,Short SS, Newman EA.
Pediatr Blood Cancer 2020 May;67(5):e28153. doi: 10.1002/pbc.28153
(PMID 32072730)
In this review of 243 children with neuroblastoma, 39% had incisional biopsy (IB) and 29% had percutaneous core needle biopsy (PCNB). PCNB was comparable to IB for obtaining a primary diagnosis and determining MYCN copy number. The yield for loss of heterozygosity and tumor ploidy was lower with PCNB versus IB.
Pancreaticoduodenectomy for the treatment of pancreatic neoplasms in children: A Pediatric Surgical Oncology Research Collaborative Study
Vasudevan SA, Ha TN, Zhu H, Heaton TE, LaQuaglia MP, Murphy JT, Barry WE, Goodhue C, Kim ES, Aldrink JH, Polites SF, Leraas HJ, Rice HE, Tracy ET, Lautz TB, Superina RA, Davidoff AM, Langham MR Jr, Murphy AJ, Bütter A, Davidson J, Glick RD, Grijalva J, Gow KW, Ehrlich PF, Newman EA, Lal DR, Malek MM, Le-Nguyen A, Piché N, Rothstein DH, Short SS, Meyers R, Dasgupta R.
Pediatr Blood Cancer 2020 Jul 13;e28425. doi: 10.1002/pbc.28425 (PMID 32658372)
In the largest series of pediatric patients undergoing pancreaticoduodenectomy (PD), PD was found to be curative for SPN and benign neoplasms. Pancreatic insufficiency is the most common postoperative complication. Outcome is primarily associated with histology.
Thoracoscopy Versus Thoracotomy for the Management of Metastatic Osteosarcoma: A Pediatric Surgical Oncology Research Collaborative Study
Lautz TB, Farooqui Z, Jenkins T, Heaton TE, Doski JJ, Cooke-Barber, Murphy AJ, Davidoff AM, Mansfield SA, Kim ES, Goodhue C, Zuber S, Vasudevan SA, LaQuaglia MP, Piche N, Le-Nguyen A, Aldrink JH, Malek MM, Siow VS, Glick RD, Rich BS, Meyers RL, Short SS, Butter A, Baertschiger RM, Fialkowski EA, Dasgupta R.
Int J Cancer 2020 Aug 20. doi: 10.1002/ijc.33264. (PMID 32818304).
In this review of 202 patients with metastatic osteosarcoma and limited pulmonary disease burden we demonstrated comparable outcomes after thoracotomy and thoracoscopy for metastasectomy. While significant selection bias in these surgical cohorts limits the generalizability of the conclusions, clinical equipoise for a randomized clinical trial in patients with oligometastatic disease is supported.
Abstracts
Practice Patterns in Palliative Site-Directed Ablative Therapy in Pediatric Oncology: a Report from the Pediatric Surgical Oncology Research Collaborative
Talbot LJ, Schechter A, Mothi SS, Ragan M, Aldrink JH, Brungardt J, Dasgupta R, Lautz TB, Moya-Mendez ME, Tracy ET, Davidoff AM, Baker J
American Academy of Pediatrics, Washington, DC, October 2023
Does Pulmonary Metastasectomy Impact Outcomes for Patients with Relapsed Ewing Sarcoma?
Reiter AJ, Huang L, Craig BT, Davidoff A, Talbot LJ, Coggins J, Smith J, Aldrink JH, Bergus KC, MacArthur TA, Polites SF, Dasgupta R, Boehmer C, Brungardt J, Malek MM, Rinehardt HN, Kastenberg ZJ, Arkin CM, Gourmel A, Piche N, Wallace M, Liang J, Lovvorn HN, Petroze RT, Gillies G, Marquat JP, Becktell K, Le HD, Favela J, Rich BS, Glick R, Seemann NM, Davison J, Parent C, Roach J, Brown EG, Doyle KE, Coakley BA, Emengo P, Merola P, Grant CN, Tirumani A, Tracy ET, Moya-Mendez ME, Lautz TB on behalf of the Pediatric Surgical Oncology Research Collaborative
International Society of Pediatric Oncology, Ottawa, Canada, October 2023
Survival Outcomes in Pediatric Patients with Metastatic Ewing Sarcoma Who Achieve a Rapid Complete Response of Pulmonary Metastases
Audra J Reiter, Lynn Huang, Brian T Craig, Lindsay J Talbot, Jennifer H Aldrink, Stephanie F. Polites, Roshni Dasgupta, Marcus M. Malek, Nelson Piche, Harold N Lovvorn, Robin Petroze, Hau D Le, Barrie S. Rich, Natashia M Seemann, Jonathan Roach, Zachary J Kastenberg, Brian A Coakley, Christa N Grant, Elisabeth T Tracy, Timothy Lautz on behalf of the Pediatric Surgical Oncology Research Collaborative
American Society of Clinical Oncology, Chicago, IL, June 2023
Comparison of Outcomes Between Surveillance Ultrasound and Completion Lymph Node Dissection in Children and Adolescents with Sentinel Lymph Node Positive Cutaneous Melanoma: a Pediatric Surgical Oncology Research Collaborative Study
Scoville SD, Stanek JR, Rinehardt H, Sutthatam P, Abdelhafeez HA, Talbot LJ, Malek M, Leraas HJ, Tracy ET, Chen SY, Kim ES, Lopyan N, Lotakis D, Ehrlich PF, Favela J, Hau DL, Davidson J, Wilson CA, Seeman NM, Osman Y, Piche N, Hoang V, Petroze R, Polites S, Lee YM, Balagani A, Dasgupta R, Aldrink JH
International Society of Pediatric Oncology, Best of IPSO Session, Barcelona, Spain, October 2022
Best of IPSO
Selected for Best of the Best in Pediatric Surgery event by Stay Current in Pediatric Surgery
Contemporary Management of Undifferentiated Embryonal Sarcoma of the Liver – a Pediatric Surgical Oncology Research Collaborative Study.
Kastenberg ZJ*, Short SS, Riehle KJ, Lautz TB, Ott KC, Murphy AJ, Mansfield S, Lal DR,Brian Hallis B, Murphy JT, Roach JP, Polites SF, Commander SJ, Tracy ET, Fialkowski EA, Seemann NS, Butter AM, Rich BS, Glick RD, Bondoc AJ, Ofori-Atta B, Presson AP, Chen SY, Zamora AK, Kim ES, Superina RA, Langham MR, Meyers RL, Dasgupta R, Baertschiger R
American Pediatric Surgical Association, San Diego CA, May 2022
An Analysis of the Incidence and Management of Pleural Effusions in Patients with Wilms Tumor: a Pediatric Surgical Oncology Research Collaborative Study
Al-Hadidi A, Sutthatarn P, Talbot L, Murphy A, Whitlock R, Condon S, Naik-Mathuria B, Utria AF, Rothstein DH, Chen SY, Wong-Michalak S, Kim ES, Short SS, Meyers RL, Kastenberg ZJ, Johnston ME, Zens T, Dasgupta R, Rinehardt HN, Malek MM, Calabro K, Piché N, Callas H, Lautz TB, McKay K, Lovvorn HN, Commander SJ, Tracy ET, Lund SB, Polites SF, Davidson J, Dhooma J, Seemann NM, Marquart JP, Gainer H, Lal DR, Rich BS, Glick RD, Kwok PE, Romao RLP, Rubalcava N, Ehrlich PF, Newman E, Diehl T, Le HD, Polcz V, Petroze RT, Aldrink JH
American Academy of Pediatrics, Virtual, October 2021
Interhospital Variability in Localization Techniques for Pulmonary Nodules in Children: a Pediatric Surgical Oncology Research Collaborative Study
Morgan KM*, Anderson KT, Dasgupta R, Baertschiger RM, Lautz TB, MacArthur TA, Polites SF, Kastenberg ZJ, Talbot L, Abdelhafeez A, Roach JP, Janek KC, Mora MC, Rubaclava N, Johnston ME, Marquart JP, Tracy ET, Rich BS, Malek MM
American Academy of Pediatrics, Philadelphia, PA, October 2021
Histologic Subtype Predicts Disparate Outcomes in Pediatric Hepatocellular Carcinoma: a Pediatric Surgical Oncology Research Collaborative Study
Short SS, Kastenberg ZJ, Wei G, Bondoc A, Dasgupta R, Tiao GM, Watters E, Heaton TE, Lotakis D, La Quaglia MP, Murphy AJ, Davidoff AM, Mansfield SA, Langham MR, Lautz TB, Superina RA, Ott KC, Malek MM, Morgan KM, Kim ES, Zamora A, Lascano D, Roach J, Murphy JT, Rothstein DH, Vasudevan SA, Whitlock R, Lal DR, Hallis B, Bütter A, Baertschiger RM,Lapidus-Krol E, Putra J, Tracy ER, Aldrink JH, Apfeld J, Le HD, Park KY, Rich BS, Glick RD, Fialkowski EA, Utria AF, Meyers RL, Riehle KJ
International Society of Paediatric Oncology, SIOP Virtual, October 2021
Inflammatory Myofibroblastic Tumor: a Multi-Institutional Study from the Pediatric Surgical Oncology Research Collaborative
Rich BS, Fishbein JS, Lautz T, Rubalcava NS, Romao TL, Naik-Mathuria B, Polites SF, Kim E, Butter A, Short SS, Malek MM, Rhee DS, Utria AF, Commander SJ, Lal D, Piche N, Murphy AJ, Rothstein DH, Dasgupta R, Glick RD.
American Society of Clinical Oncology, Chicago, IL, May 2021
Optimal Management of Children with Neutropenic Appendicitis: a Pediatric Surgical Oncology Research Collaborative Study
Many BT*, Lautz TB, Dobrozsi S, Wilkinson KH, Rossoff J, Le-Nguyen AL, Dakhallah N, Piche N, Weinschenk W, Cooke-Barker J, Goodhue C, Zamora A, Kim E, Talbot LJ, Quevedo OG, Murphy AJ, Commander SJ, Tracy ET, Short SS, Meyers RL, Rinehardt HN, Aldrink JH, Dasgupta R, Lal D.
American Pediatric Surgical Association, Orlando, FL, May 2020
Clinical and Functional Outcomes of Children Treated for Chest Wall Sarcoma: a Pediatric Surgical Oncology Research Collaborative Study
Harris CJ*, Heaton TE, Murphy AJ, Helenowski IB, Mansfield SA, LaQuaglia MP, Cavalli M, Cooke-Barber J, Donaher A, Kim ES, Zobel M, Goodhue CJ, Aldrink JH, Richards H, Malek MM, Kalsi R, Fialkowski EA, Short SS, Bleicher J, Meyers RL, Piche N, Joharifard S, Troutt M, Dasgupta R, Lautz TB.
American Pediatric Surgical Association, Orlando, FL, May 2020
Correlation between imaging and operative findings in children with pulmonary metastatic osteosarcoma undergoing thoracotomy or thoracoscopy: a Pediatric Surgical Oncology Research Collaborative Study.
Lautz TB*, Doski J, Jenkins T, Heaton T, Mansfield S, Aldrink J, Farooqui Z, Rich B, Glick R, Silva A, Lal D, Malek M, Vasudevan S, Short S, Le-Nguyen A, LaQuaglia M, Murphy A, Davidoff A, Meyers R, Dasgupta R.
International Society of Pediatric Oncology, Lyon, France October 2019
Optimization of Image-Guided Percutaneous Core Needle Biopsy For Initial Diagnostic Management of Neuroblastoma: a Pediatric Surgical Oncology Research Collaborative Study
Overman RE*, Kartal T, Many BT, Jones RE, Lautz TB, Xiao J, Lal D, Somers K, Dasgupta R, Trout M, Lewis J, Aldrink JH, Mansfield S, Short SS, Meyers R, Naik-Mathuria B, Johnson B, Vasudevan S, Butter A, Davidson J, Williams A, Newman EA
American Pediatric Surgical Association, Boston, MA, May 2019
Thoracoscopy or Thoracotomy for the Management of Metastatic Osteosarcoma - a Pediatric Surgical Oncology Research Study
Doski J, Faroqui Z, Murphy AJ, Davidoff AM, Pineda IF, Vasudevan S, Naik-Muthria B, Heaton TE, LaQuaglia MP, Gerstle JT, Piche N, Aldrink J, Mansfeld S, Lal D, Malek M, Lautz T*, Silva A, Glick R, Rich B, Short S, Meyers R, Butter A, Baertschiger, R, Jenkeins T, Dasgupta R
American Pediatric Surgical Association, Boston, MA, May 2019
Pneumonectomy for Pediatric Tumors—a Pediatric Surgical Oncology Research Collaborative Study
Polites S*, Dasgupta R, Heaton T, LaQuaglia M, Kim E, Barry W, Goodhue C, Murphy A, Davidoff A, Langham M, Meyers R, Short S, Lautz T, Glick R, Ha T, Vasudevan S, Lal D, Baertschiger R, Emr B, Malek M Jenkins T
American Academy of Pediatrics, National Conference & Exhibition, Orlando, FL, October 2018
Pancreaticoduodenectomy for the Treatment of Pancreatic Neoplasms in Children: a Pediatric Surgical Oncology Research Collaborative Study
Vasudevan S*, Ha T, Heaton T, LaQuaglia M, Barry W, Kim E, Aldrink J, Polites S, Leraas H, Lautz T, Murphy A, Davidoff A, Langham M, Butter A, Glick R, Grijalva J, Newman E, Ehrlich P, Lal D, Piche, N, Rothstein D, Short S, Meyers R, Dasgupta R
American Academy of Pediatrics, National Conference & Exhibition, Orlando, FL, October 2018