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The Use of Indocyanine Green as a Diagnostic Adjunct for Pediatric Solid Malignancies

This is a non-randomized, prospective study looking at the utility of fluorescence-guided surgery with indocyanine green (ICG) in pediatric surgical oncology. The goal of the project is to understand how ICG fluorescence may improve the anatomic delineation of both primary and metastatic malignancies in children, thereby ensuring complete resections for primary tumors as well as increasing lesion yield at the time of metastasectomy. Furthermore, the use of ICG may allow for more reliable thoraco-and laparoscopic surgical resection and obviate the need for open surgery.

The primary investigator of this study is Alexander Bondoc, MD from Cincinnati Children’s Hospital Medical Center ( The central IRB was approved at CCHMC and patients are currently being enrolled.

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